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Cancer as a Manifestation of Aberrant Chromatin Structure

In this article we review many important epigenetic changes in early carcinogenesis and discuss the possibility of these alterations being targeted for therapeutic intervention in the future. Both regional DNA methylation and global chromatin packaging are interrelated partners that function in conc...

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Bibliographic Details
Main Authors: Brock, Malcolm V., Herman, James G., Baylin, Stephen B.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586529/
https://ncbi.nlm.nih.gov/pubmed/17464240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0b013e31803c5415
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