Induction of the rat prodynorphin gene through Gs-coupled receptors may involve phosphorylation-dependent derepression and activation.

Prodynorphin transcription is activated via Gs-coupled receptors through a cyclic AMP (cAMP)-dependent pathway. Four cAMP response elements (CREs) are present within the rat prodynorphin (RD) control region, and all four CREs appear to function in RD regulation. Three CREs located upstream between -...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Collins-Hicok, J, Lin, L, Spiro, C, Laybourn, P J, Tschumper, R, Rapacz, B, McMurray, C T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358652/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8164647/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.5.2837-2848.1994
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