Induction of the rat prodynorphin gene through Gs-coupled receptors may involve phosphorylation-dependent derepression and activation.

Prodynorphin transcription is activated via Gs-coupled receptors through a cyclic AMP (cAMP)-dependent pathway. Four cAMP response elements (CREs) are present within the rat prodynorphin (RD) control region, and all four CREs appear to function in RD regulation. Three CREs located upstream between -...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Collins-Hicok, J, Lin, L, Spiro, C, Laybourn, P J, Tschumper, R, Rapacz, B, McMurray, C T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358652/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8164647/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.5.2837-2848.1994
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