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The Gain-of-Function of p53 Cancer Mutant in Promoting Mammary Tumorigenesis
Tumor suppressor p53 is critical to suppress all types of human cancers, including breast cancers. The p53 gene is somatically mutated in over half of all human cancers. The majority of the p53 mutations are missense mutations, leading to the expression of the full-length p53 mutants. Several hotspo...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2012
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3586389/ https://ncbi.nlm.nih.gov/pubmed/22824795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.299 |
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