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E-cadherin gene re-expression in chronic lymphocytic leukemia cells by HDAC inhibitors
BACKGROUND: The tumor suppressor gene E-cadherin gene is frequently silenced in chronic lymphocytic leukemia (CLL) cells and results in wnt-pathway activation. We analyzed the role of histone epigenetic modifications in E-cadherin gene silencing. METHODS: CLL specimens were treated with histone deac...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2013
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3586366/ https://ncbi.nlm.nih.gov/pubmed/23432814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-88 |
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