Effect of dabrafenib on melanoma cell lines harbouring the BRAF(V600D/R) mutations

BACKGROUND: Conventional therapeutic agents are largely unsatisfactory into the treatment of malignant melanoma. Recently, an innovative approach based on inhibitors of the mutated BRAF gene (which represents the most prevalent alteration in melanoma patients) appears very promising from the clinica...

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Autori principali: Gentilcore, Giusy, Madonna, Gabriele, Mozzillo, Nicola, Ribas, Antoni, Cossu, Antonio, Palmieri, Giuseppe, Ascierto, Paolo A
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Correspondence
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586362/
https://ncbi.nlm.nih.gov/pubmed/23317446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-17
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