Effect of dabrafenib on melanoma cell lines harbouring the BRAF(V600D/R) mutations

BACKGROUND: Conventional therapeutic agents are largely unsatisfactory into the treatment of malignant melanoma. Recently, an innovative approach based on inhibitors of the mutated BRAF gene (which represents the most prevalent alteration in melanoma patients) appears very promising from the clinica...

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Detalles Bibliográficos
Main Authors: Gentilcore, Giusy, Madonna, Gabriele, Mozzillo, Nicola, Ribas, Antoni, Cossu, Antonio, Palmieri, Giuseppe, Ascierto, Paolo A
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
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Correspondence
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586362/
https://ncbi.nlm.nih.gov/pubmed/23317446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-17
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