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Abl Kinase Constructs Expressed in Bacteria: facilitation of structural and functional studies including segmental labeling by expressed protein ligation

A great portion of tyrosine kinases are involved in cell development and their structural alteration are intimately involved in associated pathologies of development and oncology. These kinases are one of major groups of targets under investigation for molecular therapeutics. To carry out biochemica...

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Autori principali: Xu, Rong, Liu, Dongsheng, Cowburn, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586340/
https://ncbi.nlm.nih.gov/pubmed/22592215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2mb25051a
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