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Brain endogenous estrogen levels determine responses to estrogen replacement therapy via regulation of BACE1 and NEP in female Alzheimer’s transgenic mice

Estrogens have been found to improve memory and reduce risk of dementia, although conflicting results such as failure of estrogen replacement therapy for treatment of Alzheimer’s disease (AD) also has been reported. Only recently, our published human brain studies showed a depletion of brain estroge...

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Main Authors: Li, Rena, He, Ping, Cui, Jie, Staufenbiel, Matthias, Harada, Nobuhiro, Shen, Yong
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586290/
https://ncbi.nlm.nih.gov/pubmed/23180279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-012-8377-3
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