Brain estrogen deficiency accelerates Aβ plaque formation in an Alzheimer's disease animal model

Much evidence indicates that women have a higher risk of developing Alzheimer's disease (AD) than do men. The reason for this gender difference is unclear. We hypothesize that estrogen deficiency in the brains of women with AD may be a key risk factor. In rapidly acquired postmortem brains from...

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Bibliografiska uppgifter
Huvudupphovsmän: Yue, Xu, Lu, Melissa, Lancaster, Techie, Cao, Phillip, Honda, Shin-Ichiro, Staufenbiel, Matthias, Harada, Nobuhiro, Zhong, Zhenyu, Shen, Yong, Li, Rena
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2005
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1323154/
https://ncbi.nlm.nih.gov/pubmed/16365303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505203102
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