Brain estrogen deficiency accelerates Aβ plaque formation in an Alzheimer's disease animal model

Much evidence indicates that women have a higher risk of developing Alzheimer's disease (AD) than do men. The reason for this gender difference is unclear. We hypothesize that estrogen deficiency in the brains of women with AD may be a key risk factor. In rapidly acquired postmortem brains from...

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Detalhes bibliográficos
Main Authors: Yue, Xu, Lu, Melissa, Lancaster, Techie, Cao, Phillip, Honda, Shin-Ichiro, Staufenbiel, Matthias, Harada, Nobuhiro, Zhong, Zhenyu, Shen, Yong, Li, Rena
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1323154/
https://ncbi.nlm.nih.gov/pubmed/16365303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505203102
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