Expression of the plasmodial pfmdr1 gene in mammalian cells is associated with increased susceptibility to chloroquine.

Chloroquine (CQ)-resistant (CQR) Plasmodium falciparum malaria parasites show a strong decrease in CQ accumulation in comparison with chloroquine-sensitive parasites. Controversy exists over the role of the plasmodial pfmdr1 gene in the CQR phenotype. pfmdr1 is a member of the superfamily of ATP-bin...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: van Es, H H, Karcz, S, Chu, F, Cowman, A F, Vidal, S, Gros, P, Schurr, E
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1994
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC358609/
https://ncbi.nlm.nih.gov/pubmed/7511206
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