Targeting frequency for deletion vectors in embryonic stem cells.

We analyzed the gene targeting frequencies and recombination products generated by a series of replacement deletion vectors which target the hprt (hypoxanthine phosphoribosyltransferase) locus in mouse embryonic stem cells. We found that the targeting frequency of a 19.2-kb deletion was comparable t...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Zhang, H, Hasty, P, Bradley, A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358607/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8139544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.4.2404-2410.1994
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