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Targeting frequency for deletion vectors in embryonic stem cells.

We analyzed the gene targeting frequencies and recombination products generated by a series of replacement deletion vectors which target the hprt (hypoxanthine phosphoribosyltransferase) locus in mouse embryonic stem cells. We found that the targeting frequency of a 19.2-kb deletion was comparable t...

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Autors principals: Zhang, H, Hasty, P, Bradley, A
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC358607/
https://ncbi.nlm.nih.gov/pubmed/8139544
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