Topical Rapamycin Therapy to Alleviate the Cutaneous Manifestations of Tuberous Sclerosis Complex: A Double-Blind, Randomized, Controlled Trial to Evaluate the Safety and Efficacy of Topically Applied Rapamycin

BACKGROUND AND OBJECTIVES: Facial angiofibromas are disfiguring facial lesions, present in up to 80% of patients with tuberous sclerosis complex. Recent elucidation of the complex cell signaling pathways that are disrupted in tuberous sclerosis indicates that rapamycin may be successful in alleviati...

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Autori principali: Koenig, Mary Kay, Hebert, Adelaide A., Roberson, Joan, Samuels, Joshua, Slopis, John, Woerner, Audrey, Northrup, Hope
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2012
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Original Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585992/
https://ncbi.nlm.nih.gov/pubmed/22934754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2165/11634580-000000000-00000
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