Efficacy and Safety of Topical Rapamycin in Patients With Facial Angiofibromas Secondary to Tuberous Sclerosis Complex: The TREATMENT Randomized Clinical Trial

IMPORTANCE: Facial angiofibromas occur in approximately 75% of individuals with tuberous sclerosis complex (TSC), causing substantial morbidity and disfigurement. Current therapies are partially effective, uncomfortable, produce scarring, and need repeating to treat recurrence. OBJECTIVE: To evaluat...

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Vydáno v:JAMA Dermatol
Hlavní autoři: Koenig, Mary Kay, Bell, Cynthia S., Hebert, Adelaide A., Roberson, Joan, Samuels, Joshua A., Slopis, John M., Tate, Patti, Northrup, Hope
Médium: Artigo
Jazyk:Inglês
Vydáno: American Medical Association 2018
Témata:
Original Investigation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128508/
https://ncbi.nlm.nih.gov/pubmed/29800048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamadermatol.2018.0464
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