Topical Rapamycin Therapy to Alleviate the Cutaneous Manifestations of Tuberous Sclerosis Complex: A Double-Blind, Randomized, Controlled Trial to Evaluate the Safety and Efficacy of Topically Applied Rapamycin

BACKGROUND AND OBJECTIVES: Facial angiofibromas are disfiguring facial lesions, present in up to 80% of patients with tuberous sclerosis complex. Recent elucidation of the complex cell signaling pathways that are disrupted in tuberous sclerosis indicates that rapamycin may be successful in alleviati...

Full description

Saved in:
Bibliographic Details
Main Authors: Koenig, Mary Kay, Hebert, Adelaide A., Roberson, Joan, Samuels, Joshua, Slopis, John, Woerner, Audrey, Northrup, Hope
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2012
Subjects:
Original Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585992/
https://ncbi.nlm.nih.gov/pubmed/22934754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2165/11634580-000000000-00000
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items