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OP9 Bone Marrow Stroma Cells Differentiate into Megakaryocytes and Platelets

Platelets are essential for hemostatic plug formation and thrombosis. The mechanisms of megakaryocyte (MK) differentiation and subsequent platelet production from stem cells remain only partially understood. The manufacture of megakaryocytes (MKs) and platelets from cell sources including hematopoie...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Matsubara, Yumiko, Ono, Yukako, Suzuki, Hidenori, Arai, Fumio, Suda, Toshio, Murata, Mitsuru, Ikeda, Yasuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585802/
https://ncbi.nlm.nih.gov/pubmed/23469264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0058123
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