Induction of functional platelets from mouse and human fibroblasts by p45NF-E2/Maf

Determinant factors leading from stem cells to megakaryocytes (MKs) and subsequently platelets have yet to be identified. We now report that a combination of nuclear factor erythroid–derived 2 p45 unit (p45NF-E2), Maf G, and Maf K can convert mouse fibroblast 3T3 cells and adult human dermal fibrobl...

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Detalhes bibliográficos
Main Authors: Ono, Yukako, Wang, Yuhuan, Suzuki, Hidenori, Okamoto, Shinichiro, Ikeda, Yasuo, Murata, Mitsuru, Poncz, Mortimer, Matsubara, Yumiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488891/
https://ncbi.nlm.nih.gov/pubmed/22855609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-413617
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