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In Human Monocyte Derived Dendritic Cells SOCS1 Interacting with CYTIP Induces the Degradation of CYTIP by the Proteasome
CYTIP (cytohesin interacting protein) is an intracellular molecule induced in dendritic cells during maturation. CYTIP modulates the binding intensity of the adhesion molecule LFA-1. If dendritic cells are silenced for CYTIP they keep longer contacts with T-cells resulting in a lower T cell stimulat...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3585367/ https://ncbi.nlm.nih.gov/pubmed/23469018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057538 |
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