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In Human Monocyte Derived Dendritic Cells SOCS1 Interacting with CYTIP Induces the Degradation of CYTIP by the Proteasome

CYTIP (cytohesin interacting protein) is an intracellular molecule induced in dendritic cells during maturation. CYTIP modulates the binding intensity of the adhesion molecule LFA-1. If dendritic cells are silenced for CYTIP they keep longer contacts with T-cells resulting in a lower T cell stimulat...

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Detalles Bibliográficos
Main Authors: Grabher, Daniela, Hofer, Susanne, Ortner, Daniela, Heufler, Christine
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585367/
https://ncbi.nlm.nih.gov/pubmed/23469018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057538
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