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In Human Monocyte Derived Dendritic Cells SOCS1 Interacting with CYTIP Induces the Degradation of CYTIP by the Proteasome

CYTIP (cytohesin interacting protein) is an intracellular molecule induced in dendritic cells during maturation. CYTIP modulates the binding intensity of the adhesion molecule LFA-1. If dendritic cells are silenced for CYTIP they keep longer contacts with T-cells resulting in a lower T cell stimulat...

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Hlavní autoři: Grabher, Daniela, Hofer, Susanne, Ortner, Daniela, Heufler, Christine
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585367/
https://ncbi.nlm.nih.gov/pubmed/23469018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057538
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