Association of Thymidylate Synthase Polymorphisms with Acute Pancreatitis and/or Peripheral Neuropathy in HIV-Infected Patients on Stavudine-Based Therapy

BACKGROUND: Low expression thymidylate synthase (TS) polymorphism has been associated with increased stavudine triphosphate intracellular (d4T-TP) levels and the lipodystrophy syndrome. The use of d4T has been associated with acute pancreatitis and peripheral neuropathy. However, no relationship has...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Domingo, Pere, Cabeza, Maria del Carmen, Torres, Ferran, Salazar, Juliana, Gutierrez, Maria del Mar, Mateo, Maria Gracia, Martínez, Esteban, Domingo, Joan Carles, Fernandez, Irene, Villarroya, Francesc, Ribera, Esteban, Vidal, Francesc, Baiget, Montserrat
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585348/
https://ncbi.nlm.nih.gov/pubmed/23468971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057347
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge