Effects of Switching from Stavudine to Raltegravir on Subcutaneous Adipose Tissue in HIV-Infected Patients with HIV/HAART-Associated Lipodystrophy Syndrome (HALS). A Clinical and Molecular Study

HIV-1/HAART-associated lipodystrophy syndrome (HALS) has been associated with exposure to stavudine (d4T) through mitochondrial dysfunction. We performed a 48-week study to assess the effects of switching from d4T to raltegravir (RAL) on metabolic and fat molecular parameters of patients with HALS....

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Main Authors: Domingo, Pere, Gutierrez, María del Mar, Gallego-Escuredo, José Miguel, Torres, Ferran, Mateo, Gracia María, Villarroya, Joan, de los Santos, Ignacio, Domingo, Joan Carles, Villarroya, Francesc, Rio, Luis Del, Estrada, Vicente, Giralt, Marta
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935839/
https://ncbi.nlm.nih.gov/pubmed/24586518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089088
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