InterAKTions with FKBPs - Mutational and Pharmacological Exploration

The FK506-binding protein 51 (FKBP51) is an Hsp90-associated co-chaperone which regulates steroid receptors and kinases. In pancreatic cancer cell lines, FKBP51 was shown to recruit the phosphatase PHLPP to facilitate dephosphorylation of the kinase Akt, which was associated with reduced chemoresist...

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Bibliografiske detaljer
Main Authors: Fabian, Anne-Katrin, März, Andreas, Neimanis, Sonja, Biondi, Ricardo M., Kozany, Christian, Hausch, Felix
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585324/
https://ncbi.nlm.nih.gov/pubmed/23469007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057508
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