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InterAKTions with FKBPs - Mutational and Pharmacological Exploration
The FK506-binding protein 51 (FKBP51) is an Hsp90-associated co-chaperone which regulates steroid receptors and kinases. In pancreatic cancer cell lines, FKBP51 was shown to recruit the phosphatase PHLPP to facilitate dephosphorylation of the kinase Akt, which was associated with reduced chemoresist...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3585324/ https://ncbi.nlm.nih.gov/pubmed/23469007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057508 |
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