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Altered Processing of Amyloid Precursor Protein in Cells Undergoing Apoptosis

Altered proteolysis of amyloid precursor protein is an important determinant of pathology development in Alzheimer's disease. Here, we describe the detection of two novel fragments of amyloid precursor protein in H4 neuroglioma cells undergoing apoptosis. Immunoreactivity of these 25–35 kDa fra...

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Autors principals: Fiorelli, Tina, Kirouac, Lisa, Padmanabhan, Jaya
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585261/
https://ncbi.nlm.nih.gov/pubmed/23469123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057979
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