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Altered Processing of Amyloid Precursor Protein in Cells Undergoing Apoptosis

Altered proteolysis of amyloid precursor protein is an important determinant of pathology development in Alzheimer's disease. Here, we describe the detection of two novel fragments of amyloid precursor protein in H4 neuroglioma cells undergoing apoptosis. Immunoreactivity of these 25–35 kDa fra...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fiorelli, Tina, Kirouac, Lisa, Padmanabhan, Jaya
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585261/
https://ncbi.nlm.nih.gov/pubmed/23469123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057979
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