Activation of Ras-ERK Signaling and GSK-3 by Amyloid Precursor Protein and Amyloid Beta Facilitates Neurodegeneration in Alzheimer’s Disease

It is widely accepted that amyloid β (Aβ) generated from amyloid precursor protein (APP) oligomerizes and fibrillizes to form neuritic plaques in Alzheimer’s disease (AD), yet little is known about the contribution of APP to intracellular signaling events preceding AD pathogenesis. The data presente...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:eNeuro
Main Authors: Kirouac, Lisa, Rajic, Alexander J., Cribbs, David H., Padmanabhan, Jaya
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2017
Ábhair:
New Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367084/
https://ncbi.nlm.nih.gov/pubmed/28374012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0149-16.2017
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla