Cytotoxic Capacity of SIV-Specific CD8(+) T Cells against Primary Autologous Targets Correlates with Immune Control in SIV-Infected Rhesus Macaques

Although the study of non-human primates has resulted in important advances for understanding HIV-specific immunity, a clear correlate of immune control over simian immunodeficiency virus (SIV) replication has not been found to date. In this study, CD8(+) T-cell cytotoxic capacity was examined to de...

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Detalhes bibliográficos
Main Authors: Mendoza, Daniel, Migueles, Stephen A., Rood, Julia E., Peterson, Bennett, Johnson, Sarah, Doria-Rose, Nicole, Schneider, Douglas, Rakasz, Eva, Trivett, Matthew T., Trubey, Charles M., Coalter, Vicky, Hallahan, Claire W., Watkins, David, Franchini, Genoveffa, Lifson, Jeffrey D., Connors, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585127/
https://ncbi.nlm.nih.gov/pubmed/23468632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003195
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