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RNAi–Based Functional Profiling of Loci from Blood Lipid Genome-Wide Association Studies Identifies Genes with Cholesterol-Regulatory Function

Genome-wide association studies (GWAS) are powerful tools to unravel genomic loci associated with common traits and complex human disease. However, GWAS only rarely reveal information on the exact genetic elements and pathogenic events underlying an association. In order to extract functional inform...

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Detalhes bibliográficos
Main Authors: Blattmann, Peter, Schuberth, Christian, Pepperkok, Rainer, Runz, Heiko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585126/
https://ncbi.nlm.nih.gov/pubmed/23468663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003338
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