Multiple myeloma is affected by multiple and heterogeneous somatic mutations in adhesion- and receptor tyrosine kinase signaling molecules

Multiple myeloma (MM) is a largely incurable plasma cell malignancy with a poorly understood and heterogeneous clinical course. To identify potential, functionally relevant somatic mutations in MM, we performed whole-exome sequencing of five primary MM, corresponding germline DNA and six MM cell lin...

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Detalhes bibliográficos
Main Authors: Leich, E, Weißbach, S, Klein, H-U, Grieb, T, Pischimarov, J, Stühmer, T, Chatterjee, M, Steinbrunn, T, Langer, C, Eilers, M, Knop, S, Einsele, H, Bargou, R, Rosenwald, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584721/
https://ncbi.nlm.nih.gov/pubmed/23396385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2012.47
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