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Activated protein C differentially regulates both viability and differentiation of osteoblasts mediated by bisphosphonates

Activated protein C (APC) is a cytoprotective anticoagulant that can promote cutaneous healing. We examined the effect of APC on viability and differentiation of the osteoblastic line, MG63, in the presence and absence of bisphosphonates (BPs). Osteoblasts were cultured and treated for 24 or 48 h wi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, You-Jin, Jeong, Jae-Kyo, Seol, Jae-Won, Xue, Meilang, Jackson, Chris, Park, Sang-Youel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584664/
https://ncbi.nlm.nih.gov/pubmed/23412516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2013.16
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