Bisphosphonate enhances TRAIL sensitivity to human osteosarcoma cells via death receptor 5 upregulation

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), a member of the TNF superfamily of cytokines, is one of the most promising candidates for cancer therapeutics. However, many osteosarcomas are resistant to TRAIL. Bisphosphonates are very effective in the treatment of bone proble...

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Main Authors: Moon, Myung-Hee, Jeong, Jae-Kyo, Seo, Jae-Suk, Seol, Jae-Won, Lee, You-Jin, Xue, Meilang, Jackson, Christopher J., Park, Sang-Youel
Format: Artigo
Jezik:Inglês
Izdano: Korean Society for Biochemistry and Molecular Biology 2011
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Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068296/
https://ncbi.nlm.nih.gov/pubmed/21297379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2011.43.3.016
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