Inhibition of autophagy flux by sertraline attenuates TRAIL resistance in lung cancer via death receptor 5 upregulation

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a potential target for cancer therapy, owing to its ability to selectively kill cancer cells without causing significant toxicity to normal cells. However, due to the lack of death receptor expression, cancer cells can become highly...

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Опубликовано в: :Int J Mol Med
Главные авторы: Zinnah, Kazi Mohammad Ali, Seol, Jae-Won, Park, Sang-Youel
Формат: Artigo
Язык:Inglês
Опубликовано: D.A. Spandidos 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307864/
https://ncbi.nlm.nih.gov/pubmed/32626921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2020.4635
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