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Activated protein C differentially regulates both viability and differentiation of osteoblasts mediated by bisphosphonates

Activated protein C (APC) is a cytoprotective anticoagulant that can promote cutaneous healing. We examined the effect of APC on viability and differentiation of the osteoblastic line, MG63, in the presence and absence of bisphosphonates (BPs). Osteoblasts were cultured and treated for 24 or 48 h wi...

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Bibliografiske detaljer
Main Authors: Lee, You-Jin, Jeong, Jae-Kyo, Seol, Jae-Won, Xue, Meilang, Jackson, Chris, Park, Sang-Youel
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584664/
https://ncbi.nlm.nih.gov/pubmed/23412516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2013.16
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