Gomisin N enhances TRAIL-induced apoptosis via reactive oxygen species-mediated up-regulation of death receptors 4 and 5

Pharmacological studies have revealed that lignans isolated from Schisandra chinensis, including gomisin N, show anticancer, anti-hepatotoxic, anti-oxidative and anti-inflammatory activities. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an important member of the tumor necrosis...

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Main Authors: INOUE, HIROKI, WAIWUT, PORNTHIP, SAIKI, IKUO, SHIMADA, YUTAKA, SAKURAI, HIROAKI
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584564/
https://ncbi.nlm.nih.gov/pubmed/22179661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2011.1299
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