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Reactive oxygen species up-regulate p53 and Puma; a possible mechanism for apoptosis during combined treatment with TRAIL and wogonin

BACKGROUND AND PURPOSE: Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) triggers apoptotic death in a variety of cancer cells without marked toxicity to most normal cells. We previously reported that wogonin, a potent anticancer agent from a Chinese herb, up-regulates p53 in prostat...

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Bibliografiska uppgifter
Huvudupphovsmän: Lee, Dae-Hee, Rhee, Juong G, Lee, Yong J
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Publishing Ltd 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743838/
https://ncbi.nlm.nih.gov/pubmed/19438509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00245.x
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