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Zerumbone Enhances TRAIL-Induced Apoptosis through the Induction of Death Receptors in Human Colon Cancer Cells: Evidence for an Essential Role of Reactive Oxygen Species

Identification of the active component and mechanisms of action of traditional medicines is highly desirable. We investigated whether zerumbone, a sesquiterpene from tropical ginger, can enhance the anticancer effects of TRAIL. We found that zerumbone potentiated TRAIL-induced apoptosis in human HCT...

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Autori principali: Yodkeeree, Supachai, Sung, Bokyung, Limtrakul, Pornngarm, Aggarwal, Bharat B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741416/
https://ncbi.nlm.nih.gov/pubmed/19654295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1161
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