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Could MDMA Promote Stemness Characteristics in Mouse Embryonic Stem Cells via mGlu5 Metabotropic Glutamate Receptors?
OBJECTIVE: Ecstasy, or 3, 4 (±) methylenedioxymethamphetamine (MDMA), is a potent neurotoxic drug. One of the mechanisms for its toxicity is the secondary release of glutamate. Mouse embryonic stem cells (mESCs) express only one glutamate receptor, the metabotropic glutamate receptor 5 (mGlu5), whic...
Wedi'i Gadw mewn:
Prif Awduron: | , , , , |
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Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
Royan Institute
2012
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3584439/ https://ncbi.nlm.nih.gov/pubmed/23508940 |
Tagiau: |
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