The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptors

Innate immunity conferred by the type I interferon is critical for antiviral defense. To date only a limited number of tripartite motif (TRIM) proteins has been implicated in modulation of innate immunity and anti-microbial activity. Here we report the cDNA cloning and systematic analysis of all kno...

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Main Authors: Versteeg, Gijs A., Rajsbaum, Ricardo, Sánchez-Aparicio, Maria Teresa, Maestre, Ana M., Valdiviezo, Julio, Shi, Mude, Inn, Kyung-Soo, Fernandez-Sesma, Ana, Jung, Jae, García-Sastre, Adolfo
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584420/
https://ncbi.nlm.nih.gov/pubmed/23438823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.11.013
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