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The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptors
Innate immunity conferred by the type I interferon is critical for antiviral defense. To date only a limited number of tripartite motif (TRIM) proteins has been implicated in modulation of innate immunity and anti-microbial activity. Here we report the cDNA cloning and systematic analysis of all kno...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3584420/ https://ncbi.nlm.nih.gov/pubmed/23438823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.11.013 |
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