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NMDA Receptors Subserve Persistent Neuronal Firing During Working Memory In Dorsolateral Prefrontal Cortex

Neurons in the primate dorsolateral prefrontal cortex (dlPFC) generate persistent firing in the absence of sensory stimulation, the foundation of mental representation. Persistent firing arises from recurrent excitation within a network of pyramidal Delay cells. Here, we examined glutamate receptor...

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Detalhes bibliográficos
Main Authors: Wang, Min, Yang, Yang, Wang, Ching-Jung, Gamo, Nao J., Jin, Lu E., Mazer, James A., Morrison, John H., Wang, Xiao-Jing, Arnsten, Amy F.T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584418/
https://ncbi.nlm.nih.gov/pubmed/23439125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.12.032
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