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LPA activates TRPV1—and it hurts
Lysophosphatidic acid, a lipid mediator, second messenger and intermediate in lipid biosynthesis, finds a new intracellular target in TRPV1. This nonselective cation channel is also targeted by the analgesic capsaicin, which acts to desensitize the channel
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3584167/ https://ncbi.nlm.nih.gov/pubmed/22173354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.738 |
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