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The phospholipase A(1) activity of lysophospholipase A-I links platelet activation to LPA production during blood coagulation

Platelet activation initiates an upsurge in polyun­saturated (18:2 and 20:4) lysophosphatidic acid (LPA) production. The biochemical pathway(s) responsible for LPA production during blood clotting are not yet fully understood. Here we describe the purification of a phospholipase A(1) (PLA(1)) from t...

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Detalhes bibliográficos
Main Authors: Bolen, Alyssa L., Naren, Anjaparavanda P., Yarlagadda, Sunitha, Beranova-Giorgianni, Sarka, Chen, Li, Norman, Derek, Baker, Daniel L., Rowland, Meng M., Best, Michael D., Sano, Takamitsu, Tsukahara, Tamotsu, Liliom, Karoly, Igarashi, Yasuyuki, Tigyi, Gabor
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073468/
https://ncbi.nlm.nih.gov/pubmed/21393252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M013326
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