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c-jun inhibits transcriptional activation by the insulin enhancer, and the insulin control element is the target of control.

Selective transcription of the insulin gene in pancreatic beta cells is regulated by its enhancer, located between nucleotides -340 and -91 relative to the transcription start site. One of the principal control elements within the enhancer is found between nucleotides -100 and -91 (GCCATCTGCT, refer...

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Detalles Bibliográficos
Main Authors: Henderson, E, Stein, R
Formato: Artigo
Idioma:Inglês
Publicado: 1994
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC358415/
https://ncbi.nlm.nih.gov/pubmed/8264634
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