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Significance of Population Size on the Fixation of Nonsynonymous Mutations in Genes Under Varying Levels of Selection Pressure

Previous studies observed a higher ratio of divergences at nonsynonymous and synonymous sites (ω = d(N)/d(S)) in species with a small population size compared to that estimated for those with a large population size. Here we examined the theoretical relationship between ω, effective population size...

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Bibliografiske detaljer
Hovedforfatter: Subramanian, Sankar
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584012/
https://ncbi.nlm.nih.gov/pubmed/23307899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.147900
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