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Significance of Population Size on the Fixation of Nonsynonymous Mutations in Genes Under Varying Levels of Selection Pressure
Previous studies observed a higher ratio of divergences at nonsynonymous and synonymous sites (ω = d(N)/d(S)) in species with a small population size compared to that estimated for those with a large population size. Here we examined the theoretical relationship between ω, effective population size...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3584012/ https://ncbi.nlm.nih.gov/pubmed/23307899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.147900 |
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