A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase.

Autophosphorylated growth factor receptors provide binding sites for the src homology 2 domains of intracellular signaling molecules. In response to epidermal growth factor (EGF), the activated EGF receptor binds to a complex containing the signaling protein GRB2 and the Ras guanine nucleotide-relea...

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Détails bibliographiques
Auteurs principaux: Li, W, Nishimura, R, Kashishian, A, Batzer, A G, Kim, W J, Cooper, J A, Schlessinger, J
Format: Artigo
Langue:Inglês
Publié: 1994
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC358401/
https://ncbi.nlm.nih.gov/pubmed/8264620
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