A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase.
Autophosphorylated growth factor receptors provide binding sites for the src homology 2 domains of intracellular signaling molecules. In response to epidermal growth factor (EGF), the activated EGF receptor binds to a complex containing the signaling protein GRB2 and the Ras guanine nucleotide-relea...
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| Publicado en: | Mol Cell Biol |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Taylor & Francis
1994
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358401/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8264620/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.1.509-517.1994 |
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