Efficient Targeted Mutagenesis in Medaka Using Custom-Designed Transcription Activator-Like Effector Nucleases

Transcription activator-like effector nucleases (TALENs) have become powerful tools for targeted genome editing. Here we demonstrate efficient targeted mutagenesis in medaka (Oryzias latipes), which serves as an excellent vertebrate model for genetics and genomics. We designed and constructed a pair...

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Autors principals: Ansai, Satoshi, Sakuma, Tetsushi, Yamamoto, Takashi, Ariga, Hiroyoshi, Uemura, Norihito, Takahashi, Ryosuke, Kinoshita, Masato
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2013
Matèries:
Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583995/
https://ncbi.nlm.nih.gov/pubmed/23288935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.147645
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