Efficient Targeted Mutagenesis in Medaka Using Custom-Designed Transcription Activator-Like Effector Nucleases

Transcription activator-like effector nucleases (TALENs) have become powerful tools for targeted genome editing. Here we demonstrate efficient targeted mutagenesis in medaka (Oryzias latipes), which serves as an excellent vertebrate model for genetics and genomics. We designed and constructed a pair...

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Dettagli Bibliografici
Autori principali: Ansai, Satoshi, Sakuma, Tetsushi, Yamamoto, Takashi, Ariga, Hiroyoshi, Uemura, Norihito, Takahashi, Ryosuke, Kinoshita, Masato
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2013
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Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583995/
https://ncbi.nlm.nih.gov/pubmed/23288935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.147645
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