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An independent endocytic pathway stimulates different monocyte subsets by the a2 N-terminus domain of vacuolar-ATPase

The vacuolar ATPase (V-ATPase) plays an important role in tumor progression and metastases. A novel peptide from the a2 isoform of V-ATPase called a2NTD has been shown to exert an immunoregulatory role in the tumor microenvironment by controlling the maturation of monocytes toward a tumor-associated...

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Bibliographic Details
Main Authors: Kwong, Christina, Gilman-Sachs, Alice, Beaman, Kenneth
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583941/
https://ncbi.nlm.nih.gov/pubmed/23483532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.22978
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